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Date Published: 21/01/2022

ARCHIVED - Research shows CBD can prevent Covid from replicating

ARCHIVED ARTICLE

A study conducted on mice shows that CBD inhibits viral replication without side effects

<span style='color:#780948'>ARCHIVED</span> - Research shows CBD can prevent Covid from replicating

A breakthrough study published this week in the journal ‘Science Advances’ has examined the effects of cannabidiol (CBD) on human and mice cells and found that the primary active compound in hemp and marijuana (Cannabis sativa) may prevent SARS-CoV-2 replication early in the course of infection, shortly after the virus has entered the body.

In addition, an analysis of 1,212 patients from the National Covid Cohort Collaborative who had a history of taking CBD oil to treat seizures showed a substantially lower rate of Covid infection in comparison to control groups.

To test the theory, researchers from the University of Chicago treated human lung cancer cells with CBD two hours before exposing the cells to coronavirus. After 48 hours, the team observed potent inhibition of viral replication with no toxic effects. Comparable results were achieved when the substance was tested on two other human cell types and three variants of the virus (Alpha, Beta and Gamma).

Taking it a step further, the researchers then tested their results on mice that express the human ACE2 receptor – the key entry point for Covid. The rodents were injected with CBD twice a day for a week before being infected with coronavirus and for four days afterward. The results were conclusive: at both the highest and lowest doses, CBD reduced viral load in the mice with no adverse side effects.

“These results establish the preclinical efficacy of CBD as an antiviral drug for SARS-CoV-2 during the early stages of infection,” explained Long Chi Nguyen, lead author.

The team was quick to point out that the use of CBD in treating Covid must still go through rigorous testing and cautioned people against self-medicating as the optimal dosage, formulation, and mode of administration is still unclear.

Nguyen and his colleagues clarified that other similar compounds such as cannabidiolic acid (BBDA) and cannabidivarin (CBDV) produced no observable results against the virus. Moreover, it was discovered that tetrahydrocannabinol (THC), the main photoactive compound grown as marijuana, could actually strongly counteract the antiviral effects of CBD.

The authors have concluded that this finding “essentially rules out the feasibility of marijuana serving as an effective antiviral CBD source” since the purity, composition and concentration are so variable among cannabis products and commercially available CBD.

CBD is a compound that is frequently touted as a remedy for all manner of ills, mainly in the form of drops of CBD oil, and is readily available to buy online and in shops.

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Iberoptima award winning CBD vitamins & supplements supplier in Mazarron Iberoptima is a Mazarrón-based CBD oil, supplements and vitamin company which uses state-of-the-art ‘Micelle’ enhanced technology to provide the best product to their customers.

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